MTA-SE
Research groups of the Hungarian Academy of Sciences and Semmelweis University
Neurobiochemistry Research Division
Leader: Dr. Veronika Ádám
E-mail: adam.veronika@med.semmelweis-univ.hu
Institute: Department of Medical Biochemistry
Mitochondrial diseases, oxidative stress, reactive oxygen species, dihydrolipoamide dehydrogenase mutants, glycerophosphate shunt, glycerophosphate dehydrogenase.
Duration: 01.07.2013 – 30.06.2018
Weblink: https://semmelweis.hu/biokemia/scientific-research-2/neurobiochemistry-research-divisions/
Neuropsychopharmacology and Neurochemistry Research Group
Leader: Prof. György Bagdy, PhD, DSc
E-mail: bag13638@iif.hu
Institute: Department of Pharmacodynamics
The research group investigates the neurobiological pathways that play a role in the onset of depression as a result of environmental factors, as well as in the mechanism of action of antidepressant therapy. Genomic, transcriptomic, pharmacological and imaging procedures are used in the course of the research. The goal of the research is the identification of new drug targets and the improvement of personalised treatment options.
Duration: 01.07.2013 – 30.06.2018
Weblink: https://semmelweis.hu/gyogyszerhatastan/mta-se-research-group/
Pathobiochemistry Research Group
Contact: Dr. Gábor Bánhegyi
E-mail: banhegyi.gabor@med.semmelweis-univ.hu
Institute: Department of Medical Chemistry, Molecular Biology and Pathobiochemistry
Signal transduction therapy; the connection between ER stress, diabetes, and tumours.
Duration: 01.07.2017 – 30.06.2022
Immunproteogenomics Extracellular Vesicle Research Group
Leader: Prof. Edit Irén Buzás MD, PhD, DSc
E-mail: buzas.edit@med.semmelweis-univ.hu
Clinic: Department of Genetics, Cell- and Immunobiology
Extracellular vesicle-focused studies on i) basic aspects of extracellular vesicle biogenesis, ii) in silico genomics of extracellular vesicle secretion, iii) immunological studies, iv) twin studies and v) studies on circulating extracellular vesicles in patients with graft versus host disease.
Duration: 01.07.2017 – 30.06.2022.
Weblink: http://gsi.semmelweis.hu/index.php/en/research/research-groups/immunproteogenomics
Molecular Physiology Research Group
Leader: Prof. László Hunyady, MD., PhD., DSc.
E-mail: hunyady.laszlo@med.semmelweis-univ.hu
Institute: Department of Physiology
The research group investigates the functioning of a group of hormone receptors, with the aim of identifying and analysing chemicals that are capable of selectively controlling the signal reception processes of these receptors.
Duration: 01.07.2017 – 30.06.2022
Weblink: https://semmelweis.hu/elettan/research/molecular-physiology/
Molecular Medicine Research Group
Leader: Dr. Péter Igaz
E-mail: igaz.peter@med.semmelweis-univ.hu
Clinic: 2nd Department of Internal Medicine
Molecular endocrinology and gastroenterology, genetics and epigenetics of endocrine and gastrointestinal tumours, next generation sequencing, microRNAs, studies on methylation, bioinformatics.
Duration: 01.07.2017 – 30.06.2022
Weblink: https://semmelweis.hu/belgyogyaszat2/endocrine-genetics-laboratory/ https://semmelweis.hu/belgyogyaszat2/microrna-adrenal-research-group/ https://semmelweis.hu/belgyogyaszat2/molecular-gastroenterology/
Immunological and Haematological Research Group
Leader: Dr. Zoltán Prohászka
E-mail: prohaszka.zoltan@med.semmelweis-univ.hu
Clinic: 3rd Department of Internal Medicine
Duration: 01.07.2017 – 30.06.2022
Paediatrics and Nephrology Research Group
Leader: Dr. Attila Szabó
E-mail: szabo.attila@med.semmelweis-univ.hu
Clinic: 1st Department of Paediatrics
The research group aims to provide a molecular-level description of the fibrotic process of chronic diseases both localised to specific cells and affecting the entire person. The researchers primarily examine those common mechanisms that cause chronic deviation bound to the endothelium. They also pay particular attention to epithelial mesenchymal transformation. Translational research areas extend to the study of hypoxic injury, metabolic changes, disease processes affecting the cardiovascular system, and oncological changes.
Duration: 01.07.2017 – 30.06.2022
Previous MTA-SE Research Groups financed by Semmelweis University
Molecular Biophysics Research Group
Leader: Prof. Miklós Kellermayer, DSc, Dr. Med. Habil.
E-mail: kellermayer.miklos@med.semmelweis-univ.hu
Institute: Department of Biophysics and Radiation Biology
Membrane proteins
Duration: 01.07.2012 – 30.06.2017
Weblink: http://biofiz.semmelweis.hu/nanobiotech/index.php?p=m&mid=8
Molecular Oncology Research Group
Leader: Prof. József Tímár, M.D., Ph.D., D.Sc.
E-mail: jtimar@gmail.com
Institute: 2nd Department of Pathology
Molecular pathology, metastasis, experimental cancer research, microenvironment. Cancer cells as well as their interactions with the host are key determinants of the outcome of the malignant diseases. Molecular processes during the malignant transformation of normal cells are well described but those which are behind the metastatization are much less although this is what determines the prognosis of the disease. This group has a long track record of metastasis research based on what it is aimed at identifying genetic and molecular mechanisms of local dissemination and metastatization, cancer specific stromal alterations and tumour vascularization. Research is focused on the most prevalent human solid cancers (breast-, lung- and colorectal cancers), on those which can be considered orphan (melanoma, liver cancer or kidney cancer) and the unique haematological malignancies. Major aims of these translational studies are the development of novel diagnostic, prognostic and predictive markers to promote precision medicine.
Duration: 01.07.2012 – 30.06.2017