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MTA-SE Research Groups

MTA-SE
Research groups of the Hungarian Academy of Sciences and Semmelweis University


Neurobiochemistry Research Division

Leader:    Dr. Veronika Ádám
E-mail: adam.veronika@med.semmelweis-univ.hu
Institute: Department of Medical Biochemistry

Research topic

Mitochondrial diseases, oxidative stress, reactive oxygen species, dihydrolipoamide dehydrogenase mutants, glycerophosphate shunt, glycerophosphate dehydrogenase.

Duration: 01.07.2013 – 30.06.2018

Weblink: http://semmelweis.hu/biokemia/scientific-research-2/neurobiochemistry-research-divisions/

 

Neuropsychopharmacology and Neurochemistry Research Group

Leader:    Prof. György Bagdy, PhD, DSc
E-mail: bag13638@iif.hu
Institute: Department of Pharmacodynamics

Research topic

The research group investigates the neurobiological pathways that play a role in the onset of depression as a result of environmental factors, as well as in the mechanism of action of antidepressant therapy. Genomic, transcriptomic, pharmacological and imaging procedures are used in the course of the research. The goal of the research is the identification of new drug targets and the improvement of personalised treatment options.

Duration: 01.07.2013 – 30.06.2018

Weblink: http://semmelweis.hu/gyogyszerhatastan/mta-se-research-group/

 

Pathobiochemistry Research Group

Contact: Dr. Gábor Bánhegyi
E-mail: banhegyi.gabor@med.semmelweis-univ.hu
Institute: Department of Medical Chemistry, Molecular Biology and Pathobiochemistry

Research topic

Signal transduction therapy; the connection between ER stress, diabetes, and tumours.

Duration: 01.07.2017 – 30.06.2022

Weblink: http://semmelweis.hu/orvosi-vegytan/en/research/

 

Immunproteogenomics Extracellular Vesicle Research Group

Leader: Prof. Edit Irén Buzás MD, PhD, DSc
E-mail: buzas.edit@med.semmelweis-univ.hu
Clinic: Department of Genetics, Cell- and Immunobiology

Research topic

Extracellular vesicle-focused studies on i) basic aspects of extracellular vesicle biogenesis, ii) in silico genomics of extracellular vesicle secretion, iii) immunological studies, iv) twin studies and v) studies on circulating extracellular vesicles in patients with graft versus host disease.

Duration: 01.07.2017 – 30.06.2022.

Weblink: http://gsi.semmelweis.hu/index.php/en/research/research-groups/immunproteogenomics

 

Molecular Physiology Research Group

Leader:    Prof. László Hunyady, MD., PhD., DSc.
E-mail: hunyady.laszlo@med.semmelweis-univ.hu
Institute: Department of Physiology

Research topic

The research group investigates the functioning of a group of hormone receptors, with the aim of identifying and analysing chemicals that are capable of selectively controlling the signal reception processes of these receptors.

Duration: 01.07.2017 – 30.06.2022

Weblink: http://semmelweis.hu/elettan/research/molecular-physiology/

Media: http://semmelweis.hu/english/news/2013/09/the-role-of-exploratory-research-at-semmelweis-university/

 

Molecular Medicine Research Group

Leader:    Dr. Péter Igaz
E-mail: igaz.peter@med.semmelweis-univ.hu
Clinic: 2nd Department of Internal Medicine

Research topic

Molecular endocrinology and gastroenterology, genetics and epigenetics of endocrine and gastrointestinal tumours, next generation sequencing, microRNAs, studies on methylation, bioinformatics.

Duration: 01.07.2017 – 30.06.2022

Weblink: http://semmelweis.hu/belgyogyaszat2/endocrine-genetics-laboratory/ http://semmelweis.hu/belgyogyaszat2/microrna-adrenal-research-group/ http://semmelweis.hu/belgyogyaszat2/molecular-gastroenterology/

 

Immunological and Haematological Research Group

Leader:    Dr. Zoltán Prohászka
E-mail: prohaszka.zoltan@med.semmelweis-univ.hu
Clinic: 3rd Department of Internal Medicine

Research topic

Duration: 01.07.2017 – 30.06.2022

 

Paediatrics and Nephrology Research Group

Leader:    Dr. Attila Szabó
E-mail: szabo.attila@med.semmelweis-univ.hu
Clinic: 1st Department of Paediatrics

Research topic

The research group aims to provide a molecular-level description of the fibrotic process of chronic diseases both localised to specific cells and affecting the entire person. The researchers primarily examine those common mechanisms that cause chronic deviation bound to the endothelium. They also pay particular attention to epithelial mesenchymal transformation. Translational research areas extend to the study of hypoxic injury, metabolic changes, disease processes affecting the cardiovascular system, and oncological changes.

Duration: 01.07.2017 – 30.06.2022

 

Previous MTA-SE Research Groups financed by Semmelweis University


Molecular Biophysics Research Group

Leader:    Prof. Miklós Kellermayer, DSc, Dr. Med. Habil.
E-mail: kellermayer.miklos@med.semmelweis-univ.hu
Institute: Department of Biophysics and Radiation Biology

Research topic

Membrane proteins

Duration: 01.07.2012 – 30.06.2017

Weblink: http://biofiz.semmelweis.hu/nanobiotech/index.php?p=m&mid=8

 

Molecular Oncology Research Group

Leader:    Prof. József Tímár, M.D., Ph.D., D.Sc.
E-mail: jtimar@gmail.com
Institute: 2nd Department of Pathology

Research topic

Molecular pathology, metastasis, experimental cancer research, microenvironment. Cancer cells as well as their interactions with the host are key determinants of the outcome of the malignant diseases. Molecular processes during the malignant transformation of normal cells are well described but those which are behind the metastatization are much less although this is what determines the prognosis of the disease. This group has a long track record of metastasis research based on what it is aimed at identifying genetic and molecular mechanisms of local dissemination and metastatization, cancer specific stromal alterations and tumour vascularization. Research is focused on the most prevalent human solid cancers (breast-, lung- and colorectal cancers), on those which can be considered orphan (melanoma, liver cancer or kidney cancer) and the unique haematological malignancies. Major aims of these translational studies are the development of novel diagnostic, prognostic and predictive markers to promote precision medicine.

Duration: 01.07.2012 – 30.06.2017

Weblink: http://semmelweis.hu/patologia2/about-us/