Lectures
Lectures:
- Tuesday 13:10-14:20 Szent-Györgyi Albert lecture hall
- Thursday 08:00-09:10 Szent-Györgyi Albert lecture hall
Lecturers: Tretter, László MD, PhD, DSc; Kolev, Kraszimir MD, PhD, DSc; Csanády, László MD, PhD, DSc; Törőcsik, Beáta MD, PhD
| Week | Date | Topic |
| 01 | 2019.02.05 | Metabolism of red blood cells. Red blood cell enzymopathies |
| 2019.02.07 | Metabolism of muscle and heart | |
| 02 | 2019.02.12 | Metabolic characteristics of brain and adipose tissue. Metabolism of lymphocytes and intestinal epithel cells |
| 2019.02.14 | Reseach Students’ Conference | |
| 03 | 2019.02.19 | The starving-feed cyclus and its regulation. Regulattion of hepatocyte metabolism in starvation |
| 2019.02.21* | ChREBP signal transduction. The role of the SREBP, mTOR and PPAR system in the regulation of metabolism | |
| 04 | 2019.02.26* | AMP kinase, PGC1-a, HIF, p53. The role of thyroid hormones |
| 2019.02.28 | Na+,K+ ATP-ase. The permeability of cell membranes, P-type ATP-ase. Structure of Na+,K+ ATP-ase, Na+,K+ ATP-ase isoforms. Regulation. Secondary active transports. Na-H exchange | |
| 05 | 2019.03.05 | Chemical neurotransmission. Cholinergic neurotransmission. Biosynthesis of acetylcholine. receptors, acetylcholine esterase. Molecular mechanism of exocytosis |
| 2019.03.07 | Noradrenerg neurotransmission. Synthesis and metabolism of norepinephrine. Synaptic uptake. | |
| 06 | 2019.03.12 | Adrenerg receptors. Molecular mechanism of epinephrine and norepinephrine on various organs |
| 2019.03.14 | Dopaminergic and serotoninergic neurotransmission. Synthesis, transporters, receptors. Biochemistry of Parkinson disease | |
| 07 | 2019.03.19 | Glutamatergic neurotransmission |
| 2019.03.21 | NO: Regulatory role of NO. Nitric oxide synthase. Guanylate cyclase. Molecular effects of nitric oxide | |
| 08 | 2019.03.26* | General properties of ion channels. Methods for studying ion channels. Molecular mechanisms of gating and permeation. Structure of K+ channels. (LCs) |
| 2019.03.28* | Molecular diversity of ion channels. Voltage-gated K+ channels. ATP-sensitive K+ channels. Voltage-gated Cl- channels. The CFTR chloride channel. The nicotinic Acetylcholine Receptor. (LCS) | |
| 09 | 2019.04.02 | General overview of blood clot formation and elimination. Fibrinogen and fibrin. Prothrombin activation and regulation of thrombin activity. Triggers of blood clotting, amplification of the initiation. (KK) |
| 2019.04.04 | Inhibitors of blood coagulation and negative feedback mechanisms (KK) | |
| 10 | 2019.04.09 | Fibrinolysis. Activation of plasminogen. Inhibitors of plasmin (KK) |
| 2019.04.11 | Cellular elements of the haemostatic system. Platelets and von Willebrand factor (KK) | |
| Spring break, Eastern | ||
| 11 | 2019.04.23 | Neutrophils and endothelial cells in haemostasis. (KK) |
| 2019.04.25 | Haemodynamical and biochemical interactions in haemostasis (KK) | |
| 12 | 2019.04.30 | Faculty Day (FD) |
| 2019.05.02* | The role of endothelial dysfunction in atherosclerosis. LDL oxidation and pattern-recognition receptors (TLR, scavenger receptors). Cholesterol induced pyroptosis (KK) | |
| 13 | 2019.05.07* | Effect of cholesterol on atherosclerotic plaque formation. Risk factors of atherosclerosis related to cholesterol homeostasis (diabetes, hypertriglyceridemia). Biochemical background of atherosclerosis, prevention) |
| 2019.05.09* | Signaltransduction-1: Therapeutic targeting of signal transduction pathways (TB) | |
| 14 | 2019.05.14* | Signaltransduction-2: Cytokine signaling. Jak-STAT pathway. Calcium signaling. Nuclear receptors. (TB) |
| 2019.05.16* | Signaltransduction-3: Wnt signal transduction pathways. Frizzled/Arrow/LRP receptors, Dsh, axin, APC proteins, GSK3, CK1α protein kinases, protein phosphatases (PP2A) and the ubiquitin system. Notch receptor signaling (TB) |
*facultative lectures held for dentistry students
Groups
Laboratory and seminar lessons in spring semester of the 2018/2019 academic year
| Day | Time | Group | Lab teacher |
Room# |
| Wednesday | 08:00-10:30 | ED01 | Vér, Ágota | 1 |
| Wednesday | 08:00-10:30 | ED02 | Vér, Ágota | 1 |
| Wednesday | 08:00-10:30 | ED03 | Végh, Miklós | 2 |
| Wednesday | 08:00-10:30 | ED04 | Végh, Miklós | 2 |
| Wednesday | 08:00-10:30 | ED05 | Bak, Judit | 3 |
Laboratory lessons
Laboratory lessons and seminars are held at laboratory rooms of the Deparment (EOK-Building, Budapest IX., Tűzoltó utca 37-47. H-1094, 1st floor, passage ‘C’)
| 01 | 2019.02.06 | F1-2-3-4-5 | Metabolism of excercise (sem) |
| 02 | 2019.02.13 | ||
| 03 | 2019.02.20 | F1-2-3-4-5 | Determination of transaminase enzyme activity. (lab) Determination of serum creatine kinase activity (lab) |
| 04 | 2019.02.27 | ||
| 05 | 2019.03.06 | F1-2-3-4-5 | Extracellular matrix (sem) |
| 06 | 2019.03.13 | F1-2-3-4-5 | First midterm exam |
| 07 | 2019.03.20 | F1-2-3-4-5 | Acute and chronic liver disease (sem) |
| 08 | 2019.03.27 | F1-2-3-4-5 | Retake of first midterm exam |
| 09 | 2019.04.03 | F1-2-3-4-5 | Determination of blood glucose level; In vitro determination of hemoglobin 1Ac (lab) |
| 10 | 2019.04.10 | F1-2-3-4-5 | Second midterm exam |
| SPRING BREAK, EASTER | |||
| 11 | 2019.04.27 | F1-2-3-4-5 | Experimental models of blood coagulation (lab) |
| 12 | 2019.05.01 | F1-2-3-4-5 | MAY DAY – Retake of second midterm exam. Date, time, location is published later |
| 13 | 2019.05.08 | F1-2-3-4-5 | Haemostatic abnormalities 1-2 (sem) |
| 14 | 2019.05.15 | F1-2-3-4-5 | Second retake exam of mirterm exams#1 and #2 |
Recommended books
- Harper’s Illustrated Biochemistry (31st edition)
- Powerpoint files of lectures
- Consultation manual
- Students’ own notes
- Ask your laboratory teacher for the username and password of our authorized pages
Midterm exams
- 1st midterm exam: 13th of March, 2019; 08:00-10:30
- 2nd midterm exam: 10th of April, 2019; 08:00-10:30
- Retake of 1st midterm exam: 27th of March, 2019; 08:00-10:30
- Retake of 2nd midterm exam: date and location is published later
- 2nd retake of the 1st and 2nd midterm exams: 15th of May, 2019; 08:00-10:30
Competition
Dental Biochemistry 3 competition is held on the 14th week:
May 13, 2019 at 17:30, Szent-Györgyi Albert lecture hall.
Material: lectures, seminars and laboratory lessons of the fall and spring semesters of 2018/2019 and spring semester of the 2017/2018 academic year
Test: biochemistry problems and structures (max. 30 + 10) + 70 multiple choice type questions
Students reaching at least 75 % will be exempted from the examination by mark 5
Other exemptions are not possible
Conditition:
- grade 3 or better at both midterms
- registration for the subject matter of Dental Biochemistry 3 in the spring semester of 2018/2019 academic year
- registration for the subject matter of Dental Biochemistry 2 in the fall semester of 2018/2019 academic year
- registration for the subject matter of Dental Biochemistry 1 in the fall semester of 2017/2018 academic year
Registration: May 8-10, 2019
Topic list
- Topics (dentistry students – new) topic list for students of dental biochemistry III (NEW CURRICULUM)
- Topics (for students of old curriculum) topic list for medical and dentistry students of (medical) biochemistry, molecular and cell biology III (OLD CURRICULUM)
Final examination
Course-outline: Dental Biochemistry 3
Spring semester of 2018/2019 academic year
Head of Deparment of Medical Biochemistry: Prof. Tretter, László MD, PhD, DSc
- Subject title: Dental biochemistry 3
- Faculty: Dentistry
- Code: FOKOOBI204_3A
- Credit: 3
Student office of Department of Medical Biochemistry
Budapest IX., Tűzoltó utca 37-47 H-1094; ROOM: 1.508
+36-1-459-1500#60061; +36-20-666-60061
Office hours: Tuesday, Wednesday, Thursday – 10:00-12:00
Course-coordinator for medical biochemistry 1-2-3, dental biochemistry 1-2-3 students:
István Léránt PhD., +36-20-663-2267
| Mr. Zsolt Ozsváth | Mrs Vera Pichler |
| +36-20-666-0061 | +36-20-666-0061 |
| medical & dental biochemistry 3 | medical & dental biochemistry 1 |
| medical & dental biochemistry 2 |
“English Secretariate”
| Dentistry students | Medical students |
| Mrs Borbála Hanek | Adrienn Bácskai |
| +36-20-666-0479 | +36-20-666-0072 |
| Dental biochemistry 2-3 | Medical biochemistry 2-3 |
| Dental biochemistry 1 | Éva Kiss |
| +36-20-666-0481 | |
| Medical biochemistry 1 |
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