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BIOCHEMISTRY II (Pharmacy) 2018/2019


Lecturers: Kraszimir Kolev MD, PhD, DSc (KK); Erzsébet Tóth (ET) Beáta Törőcsik MD, PhD (BT); László Tretter MD, PhD, DSc (LT); Attila Ambrus PhD (AA); Pál Bauer PhD (PB)

Wednesday 15:15-17:30 Seminar room#1 in EOK Building
01 2018.09.12 Haemostasis  I KK
02 2018.09.19 Haemostasis  II  KK
03 2018.09.26 Metabolism of xenobiotics and selected endogenous molecules ET
04 2018.10.03 Signal transduction BT
05 2018.10.10 Neurobiochemistry I ET
06 2018.10.17 Neurobiochemistry II ET
07 2018.10.24 Metabolic integration I  LT
08 2018.10.31 Metabolic integration II LT
09 2018.10.07 Metabolism of nucleotides AA
10 2018.10.14 DNA replication and repair BT
11 2018.10.21 Molecular biology technics PB
12 2018.10.28 Molecular biology technics PB
13 2018.12.05 Cell cycle, cell death PB 
14 2018.12.12 Tumors LT

Laboratory lessons / Seminars

01 2018.09.14 Safety rules. Succinate dehydrogenase activity measurement 
04 2018.10.05  Blood coagulation
05 2018.10.12 Piruvate dehydrogenase isoenzymes. Midterm exam I
07 2018.10.26 Mitochondrila oxidation
09 2018.11.09 LiDS-PAGE of proteins, retake on FRIDAY
11 2018.11.23 Determination of serum cholesterol and triglycerides
12 2018.11.30 Midterm exam II
13 2018.12.08 Glutamate dehydrogenase: enzyme kinetic characterization 2nd midterm retake
14 2018.12.15 Retake of both midterm exams


EP01 Friday 08:00_10:30 Tóth, Erzsébet dr

Laboratory lessons are held on every other Friday at laboratory rooms of the Department (EOK-Building, Budapest IX., Tűzoltó utca 37-47. H-1094, 1st floor, passage ‘C’)

Midterm exams

The first obligatory midterm exam: on week 5 during the practice before/after the experiments. Material: 4 questions from the lecture material from weeks 1-4, and one question from the practice. The Practice Instructor gives and corrects the assay and open questions. Retakes are on weeks 9 and 14 for the students who failed or were absent during the first occasion. Successful midterms can be repeated only once.
The second obligatory midterm: on week 12 in extra time. Type of questions: multiple choices. Materials: lectures from weeks 5-12, plus one assay question on the practice. Retakes are on weeks 13 and 14 for the students who failed or were absent during the first occasion. Successful midterms can be repeated only once.
Passing both midterms is a requirement for the signature of the semester. The grade 4 or 5 from either or both of the Midterms entitles the students for partial exemptions in their final exams (see below).

Evaluation of the midterms:

5 points can be given for each question in Midterm I. In Midterm II 25 points can be collected for the 25 multiple choice questions plus 5 points can be gained for the practice question.

0-9: fail
10-13: satisfactory
14-17: fair
18-21: good
22-25 or 30 (in Midterm II): excellent

Final exam

This is a written exam from the materials of the two semesters.
2 blocks from the material of the first semester (multiple choice) 2 × 10 points (Blocks 1&2)
2 blocks from the material of the second semester (multiple choice) 2 × 10 points (Blocks 3&4)
Block 5: a question on the theory of one lab practice – 5 points
The last part will ask the material of the last three lectures (multiple choice) – 5 points (Block 6).
50 points can be collected in total. Students need to collect a minimum of 40% in each block (Blocks 1-6) to pass this exam. Those students who received the mark 4 for either (or both) of their Midterm I or (and) II will get 8 (or 16) points for Block 3 or (and) 4, respectively; these students still have a choice to complete the respective exam questions to improve their grades, however, in that case these points will be counted for the exam (even if they are less than 8 (or 16)). The same policy applies to the Midterm grades of 5 with 10 (or 20) points. This offer is valid only in the respective examination period and cannot be carried over (e.g. in case of a repetition of the semester or a CV exam). Students cannot carry over any exemption from Semester I (everybody needs to answer the Biochemistry I questions).


0-19 (or <40% from any of the blocks, Block 1-6)           Fail
20-27 (and ≥40% from every single block)          Pass
28-35   Fair
36-43   Good
44-50   Excellent

The exam results will be published in the Neptun system on the same or the following day of the exam. Modifying exam dates is free in Neptun, but only up until two days before the exam. In case a student cannot come to the exam, but brings a justification for his/her absence in 3 days, we withdraw the name from the official exam list; otherwise the „absent from the exam” note will be written into the index book. Retake of a failed exam or reparation of a passed exam is possible only 3 days after the previous exam.

Teaching material: Berg-Tymoczko-Stryer: Biochemistry 8th edition

Course material: lecture slides with personal lecture notes

Recommended books

  • Harper’s Illustrated Biochemistry (30th edition)
  • Powerpoint files of lectures
  • Consultation manual 
  • Students’ own note


Prerequisites: Organic Chemistry II (GYSZKSZKE2A), Biochemistry I (GYOBIBIKE1A)
Students can register to Biochemistry II if they possess successful examinations from all the prerequisite subjects. Students transferring from any other University may register, too, if their previous education history qualifies them to do so; the decision is the exclusive right of the Lecturer of Biochemistry. The possibility of acceptance of a previous completion and/or a mark of any Biochemistry courses taken at another University will also be examined by the Lecturer and will be decided on the basis of the student’s official credentials (only original and authorized paperwork will be accepted) and the similarities between curricula in question. ERASMUS students may also register if they have completed the prerequisite subjects of Semmelweis University in their home institutions. Both midterms must be passed.

Conditions for acceptance:

Absence note is not required, but a maximum of one absence is permitted from practices due to any reason.

Knowledge testing during the semester: two obligatory written midterm examinations

Requirements of the signature at the end of the semester: successfully completed midterms, meeting attendance requirements

Performance control in the examination period: written final exam

Written semifinal exam: multiple choice questions


Subject matter: Dental Biochemistry 2

  • Fall semester of 2018/2019 academic year
  • Head of Deparment of Medical Biochemistry: Prof. Tretter, László
  • Subject title: Biochemistry II Faculty: Pharmaceutical Sciences
  • Code: GYOBIBIKE2A and GYOBIBIKG2A Credit: 3 Lec.:   Lab.:  
  • Teaching secretary: Tóth, Erzsébet dr +36-1-459-1500#60066
  • Students Affairs Secretary: Mrs Bökönyi, Erzsébet EOK Building, 1st Floor, Passage ‘C’; +36-1-459 -1500#60061 +36-20-663-2631
  • Prerequisites for registration to Biochemistry I: successful examination from Biochemistry I and Organic Chemistry II.