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Biochemistry 1 (Pharmacy)

Lectures

  • Monday 915-1055 in EOK ground floor seminar room, No. 1-2
  • Wednesday 1230-1315 in EOK ground floor seminar room No. 1

Semmelweis University, EOK, 37-47 Tűzoltó Street, 1094, Budapest 

Lecturers: Attila Ambrus (AA), István Léránt  (IL),  Erzsébet Tóth (ET)

  Date Topic of lectures
01 2018.02.05 Protein composition and structure (AA)
  2018.02.07 Exploring proteins and proteones (AA)
02 2018.02.12

Exploring proteins and proteomes, Basic concepts of enzymes (AA)

  2018.02.14 Basic concepts of enzymes, enzyme kinetics (AA)
03 2018.02.19 Catalytic strategies (AA)
  2018.02.21 Enzyme regulatory strategies I (AA)
04 2018.02.26 Enzyme regulatory strategies  II, myoglobin, haemoglobine (AA)
  2018.02.28 Myoglybin, hemoglobin (AA)
05 2018.03.05 Metabolism: basic concept and design. Carbohydrates (ET)
  2018.03.07 Carbohydrates (ET) 
  2018.03.07 First midterm examination before the lecture 11:30-12:30 in seminar room #6
06 2018.03.12 Glycolysis (ET)
  2018.03.14 Gluconeogenesis, fructose, galactose (ET)
07 2018.03.19 PDH complex, citric acic cycle  (ET)
  2018.03.21 Oxidative phosphorylation (ET) 
  2018.03.21 Midterm retake before the lecture 11:30-12:30
    Spring holiday (2018.03.26-2018.03.30)
08 2018.04.02 Easter Monday
  2018.04.04 Pentose phosphate pathway (ET)
09 2018.04.09 Pentose phosphate pathway, glycogen metabolism (ET)
  2018.04.11 Glycogen metabolism, (ET)
10 2018.04.16 Fatty acid degradation, ketone body metabolism (IL)
  2018.04.18 Fatty acid synthesis (IL)
  2018.04.21 Fatty acid synthesis, triglycerides (IL) (Saturday, 09:15-10:55)
11 2018.04.23 Phospholipids and cholesterol (IL)
  2018.04.25 Cholesterol and bile metabolism (IL)
12 2018.04.30 no lecture
  2018.05.02 Lipoproteins (IL)
  2018.05.02 2nd midterm (11:30-12:30)
13 2018.05.07 Lipoproteins, steroids (IL)
  2018.05.09 Protein turnover and amino acid catabolism (ET)
  2018.05.09 2nd midterm retake (11:30-12:30)
14 2018.05.14 Amino acid degradation and synthesis (IL)
  2018.05.16 Amino acid synthesis (IL)
  2018.05.16 Retake of the 1st and/or 2nd midterm exam. 11:30-12:30

Midterm exams

There are two obligatory midterms on the 5th and the 12th weeks, which are not held in the times of the lectures, but on Wednesday after the lecture in seminar room No. 1. The midterms cover lecture material until the previous weeks. In each midterm 25 points can be collected by solving 25 multiple choice questions. 44-50 points from the two midterms together and ≥19 points separately entitle the student to get the mark of 5 (excellent) as the semifinal exam grade. For 38-43 points together and ≥19 points separately we offer the mark of 4 (good) as the semifinal exam grade, although, these students have a choice to still take the written semifinal exam to improve to the excellent grade. However, such students have to accept the mark they get at the semifinal exam, even if it is worse than the good mark (including fail). In case of absence or failure (<13 points/midterm) either or both midterms may be retaken two times (each): on the 6th week the 1st Midterm, on the 13th week the 2nd and on the 14th week both midterms can be repeated on Wednesday (13.15 -13.45). Successful midterms can be repeated only once. The exam exemptions are valid in the whole examination period, but they are lost in the following examination periods.

Midterm grading
0-12 fail
13-15 satisfactory
16-18 fair
19-21 good
22-25 excellent

Requirements

Students can register to Biochemistry I if they possess successful examinations from all the prerequisite subjects. Students transferring from any other University may register, too, if their previous education history qualifies them to do so; the decision is the exclusive right of the Lecturer of Biochemistry. The possibility of acceptance of a previous completion and/or a mark of any Biochemistry courses taken at another University will also be examined by the Lecturer and will be decided on the basis of the student’s official credentials (only original, English and authorized paperwork will be accepted) and the similarities between the curricula in question. ERASMUS students may also register if they have completed the prerequisite subjects of Semmelweis University in their home institutions.
Both midterms must be passed with at least 13 points and the absences cannot be more than it is allowed in the Rules of Education and Examination.

Semifinal exam

There is a written semifinal exam with questions as follows: assays, reactions with formulae, multiple choice and sentence completion.

Exam grading
0-24 fail
25-31 satisfactory
32-37 fair
38-43 good
44-50 excellent

Results will be published in the Neptun system on the same or the following day. Modifying exam date is free in Neptun, but only until two days before the exam. In case a student does not come to the exam, but brings a justification for the absence in three days, we withdraw the name from the official exam list; otherwise the „absent from the exam” note will get into the index book. Retake of a failed exam or reparation of a passed exam is possible only after three days.

Recommended materials to study

In the midterms and the exams we ask only the lecture material back. Please, use the lecture slides, which are available from our website, together with your lecture notes. The official text book of the course is Berg-Tymoczko-Gatto-Stryer: Biochemistry, 8th edition. Almost all lectures use this textbook throughout the year; most of the figures in the lecture slides are also from this  book (or its previous editions). If a student is interested in Biochemistry in more details than it is asked at the exams, he or she is advised to also buy and use the supporting materials (including the website) of this textbook.

Course-outline: Biochemistry I (Pharmacy)

  • Neptun code: GYOBIBIKE1A
  • Credit points: 3
  • Lecturer: Dr. Attila Ambrus, Ph.D., assistant professor
  • Teaching secretary: Dr. Erzsébet Tóth, associate lecturer
  • Administrator: Mr Zsolt Ozsváth,  in EOK room 1.508, tel: +36-1-4591500, ext. 60061
  • Prerequisites for registration to Biochemistry I: successful examination from Biology II, Biophysics II, and Organic Chemistry I.
  • Weekly schedule for 14 weeks: Lectures: 3×45 min (2×45 min + 1×45 min)
  • Semester: February 5, 2018 – May 18, 2018
  • Exam period: May 22, 2018  – July 6  – 2018

Holidays:

  • February 7-9 2018, Students Research Conference
  • March 15 National Day
  • March, 26 – April 2, 2018 spring holiday + Eastern
  • April 24, 2018 – Faculty day
  • May 1, 2018 – May Day

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