BIOCHEMISTRY 2 – fall semester of 2016/2017 academic year
- Name of the subject: Biochemistry II
- Neptun-code: GYOBIBIKE2A and GYOBIBIKG2A
- Credit points: 3
- Name of the lecturer: Attila Ambrus PhD, assistant professor
- Teaching secretary: Erzsébet Tóth Pharm D., associate lecturer
- Administrator: Zsolt Ozsváth in EOK room 1.508, tel: +36-1-459-1500 ext. 60061, +36-20-666-0061
LECTURES – fall semester of 2016/2017 academic year
Wednesday 1510-1715 in EOK (37-47 Tűzoltó Str.) seminar room No. 1 (Budapest IX., Tűzoltó utca 37-47, H-1094)
Lecturers: Attila Ambrus (AA) Pál Bauer (PB), István Léránt (IL), Erzsébet Tóth (ET), László Tretter prof (LT)
|Week||Date||Topic of lectures|
|01||Sept 07||Haemostasis I (IL)|
|02||Sept 14||Haemostasis II (IL)|
|03||Sept 21||Metabolism of xenobiotics and some endogenous molecules (ET)|
|04||Sept 28||Signal transduction (PB)|
|05||Oct 05||Neurochemistry (ET)|
|06||Oct 12||Metabolic integration (LT)|
|07||Oct 19||Metabolic integration (LT)|
|08||Oct 26||DNA, RNA, flow of genetic information (AA)|
|09||Nov 02||Genomics. Bioinformatics (AA)|
|10||Nov 09||DNA replication and repair (AA)|
|11||Nov 16||RNA synthesis, regulation of gene expression (AA)|
|12||Nov 23||Protein synthesis (AA)|
|13||Nov 30||Cell cycle. Cell death (PB)|
|14||Dec 07||Tumors (LT)|
Practice – fall semester of 2016/2017 academic year
- Every other Friday 10:45 – 13:15 in EOK biochemistry laboratory room #5 of the Deparment of Medical Biochemistry (EOK-Building, Budapest IX., Tűzoltó utca 37-47. H-1094, 1st floor, passage ‘C’)
- Instructor: Erzsébet Tóth dr.
|Week||Date||Topic of laboratory lesson|
|01||Sep 09||Safety rules for work in the laboratory , Experimental model of blood coagulation|
|03||Sep 23||Competitive inhibition of succinate dehydrogenase|
|05||Oct 07||Oxidative phosphorylation in mitochondria|
|08||Oct 21||Pyruvate kinase isoenzymes, midterm exam I|
|09||Nov 04||Protein LDS PAGE|
|11||Nov 18||Determination of serum cholesterol and triglyceride|
|12||Nov 25||Midterm II|
|13||Dec 02||Purification of trypsin by affinity & Substrate specificity of trypsin and chymotrypsin. after the practice: retake of the 2nd midterm|
|14||Dec 09||Retake of both midterm exams|
Midterm exams – fall semester of 2016/2017 academic year
- The first obligatory midterm exam: on week 7 during the practice before / after experiments.
- Material: 4 questions about the lectures form weeks 1-5. and one practice question.
- The practice instuctor gives and corrects the assay and open questions.
- Retakes are on weeks 9 and 14.
- The second obligatory midterm: on week 12 in extra time. Retake on Friday. Type of questions: multiple choices.
- Material: lectures from weeks 6-12, plus one assay question about the practice.
- Retakes: are on weeks 13 and 14.
Passing both midterms is a requirement for the signature of the semester. The grade 4 or 5 form either or both of the miterms entitles the students for partial exeption of their final exams (see below)
Evaluation of the midterms 5 points can be given for each question in midterm I. In midterm II 25 points can be collected for the 25 multiple choice questions plus 5 points can be gained for the practice question.
|22-25 or 30 (in Midterm II)||5 (excellent)|
Final examination – fall semester of 2016/2017 academic year
This is a written exam from the materials of the two semesters.
- Blocks 1&2. 2 blocks from the material of the first semester (multiple choice and open questions) 2 × 10 points
- Blocks 3&4. 2 blocks from the material of the second semester (multiple choice and open questions) 2 × 10 points
- Block 5. a question about the theory of one lab practice – 5 points
- Block 6. The last part will ask for reactions with formulas and the materials of the last three lectures – 5 points
- 50 points can be collected in total.
- Students need to collect a minimum of 40% in each block (Blocks 1-6) to pass this exam.
- Those students who received the mark 4 for either (or both) of their Midterm I or (and) II will get 8 (or 16) points for Block 3 or (and) 4, respectively; these students still have a choice to complete the respective exam questions to improve their grades, however, in that case these points will be counted for the exam (even if they are less than 8 (or 16)).
- The same policy applies to the Midterm grades of 5 with 10 (or 20) points. This offer is valid only in the respective examination period and cannot be carried over (e.g. in case of a repetition of the semester or a CV exam).
- Students cannot carry over any exemption from Semester I (everybody needs to answer the Biochemistry I questions).
|0-19||(or < 40 % from any of the blocks, block 1-6)||1 (fail)|
|20-27||(and ≥ 40 % from every single block)||2 (satisfactory)|
The exam results will be published in the Neptun system on the same or the following day of the exam. Modifying exam dates is free in Neptun, but only up until two days before the exam. In case a student cannot come to the exam, but brings a justification for his/her absence in 3 days, we withdraw the name from the official exam list; otherwise the „absent from the exam” note will be written into the index book. Retake of a failed exam or reparation of a passed exam is possible only 3 days after the previous exam.
Requirements for the acknowledgement of semester
Requirements for the acknowledgement of semester –
Absence note is not required, but a maximum of two absences are permitted from practices due to any reason.
Knowledge testing during the semester: two obligatory written midterm examinations
Requirements of the signature at the end of the semester: successfully completed midterms, meeting attendance requirements
Performance control in the examination period: written final exam
There is a written semifinal exam with questions as follows: assays, formulae, multiple choice and sentence completion.