Research Group for Cerebral Cortical Modularity

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Research interest

The continuous sheet of the cerebral cortex, the so called neocortex or isocortex, is parceled both vertically and horizontally. Horizontally, the cortex is a complex network of structurally and functionally heterogeneous areas. The unique characteristic of this network is that it is formed by populations of closely spaced neurons with convergent or overlapping afferents. Thereby connections of focal regions appear as modular or patch-like pattern both within and between the areas. Similarly, cortical activations are spatiotemporally delineated forming a distributed modular architecture in the functioning brain. As such, modular organization represents the transition from the micro circuits to the large scale network. In some areas the modular connectional architecture corresponds to the known columnar cortical organization, such that certain kinds of columns are selectively connected to each other. However, in most of the cases connectional preferences of the neuronal populations are not known. A major obstacle in understanding the functioning of the cerebral cortex is that the modular connectional architecture is largely unexplored.

Major topics – see in pdf

Collaborations:

Anna W Roe, Vanderbilt University, Nashville, TN, USA
https://my.vanderbilt.edu/annaroe/

Caroline Fonta, CNRS, CerCo, Toulouse, France
http://cerco.ups-tlse.fr/Caroline-Fonta?lang=fr

Dragana Bajic, Universty of Novi Sad, Novi Sad, Serbia
http://www.ktios.net/index.php/clanovi-katedre/1370-dragana-bajic-en.html

Roland Nitschke, Albert-Ludwigs-University, Freiburg, Germany
http://www.imaging.uni-freiburg.de/team.php